Buy 5F-AB-PINACA online
It also known as 5-Fluoro-AB-PINACA is an indazole-based synthetic cannabinoid that is derived from a series of compounds originally developed by Pfizer in 2009 as an analgesic medication. This chemical has been reported to be a potent agonist of the CB1 receptor and CB2 receptor with EC50 values of 0.48 nM and 2.6 nM respectively. Buy 5F-AB-PINACA online
SUBSTANCE IDENTIFICATION:
It has formal name: N-[(2S)-1-amino-3-methyl-1-oxobutan-2-yl]-1-(5-fluoropentyl)indazole-3-carboxamide is a white powder. The chemical formula is C18H25FN4O2 with a molecular weight of 348.422 g/mol and a 99% purity with a melting point of 85.3 °C.
EFFECT AND DOSAGE
Since 5F-AB-PINACA is the fluorinated derivative of AB-PINACA, and the latter is being used as a synthetic cannabinoid in so-called ‘Spice’ mixtures, intended to mimic the psychoactive effects of cannabis, it seems plausible that this chemical is also used as a legal alternative to herbal cannabis.
TOXICOLOGY
We have not data concerning the toxicity, reproductive impact and carcinogenic/mutagenic potential of this chemicals.
Buy 5F-AB-PINACA
Objectives
We determined convulsant effects of SCRAs AB-PINACA, and 5F-ADB-PINACA in adult male NIH Swiss mice, and then determined if convulsant effects of AB-PINACA, 5F-AB-PINACA, 5F-ADB-PINACA, and JWH-018 elicited seizure-like effects using EEG.
Methods
Mice were administered SCRAs or pentylenetetrazole (PTZ) and placed in observation chambers where convulsant effects were scored. The capacity of the CB1R antagonist rimonabant, the benzodiazepine diazepam, or the non-specific CYP450 inhibitor 1-aminobenzotriazole (1-ABT) to attenuate convulsant effects was determined. Other mice were prepared with EEG headmounts to ascertain whether observed convulsions occurred concurrently with seizure-like effects by assessing root-mean-square (RMS) power, high amplitude EEG spike analysis, and videography.

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