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Buy 2′-OXO-PCE Online
2-Oxo-PCE (Deschloro-N-ethyl-Ketamin / O-PCE) is a dissociative substance that is closely related to Deschloroketamin and is mainly considered to be an MXE substitute (similar to Methoxphenidine, MXP or Diphenidine). Buy 2′-OXO-PCE Online
Form and quantity per Order unit of 2-Oxo-PCE
1000 milligrams of powder, pure substance with a purity of at least 98% per order unit.
What is 2′-OXO-PCE?
2′-Oxo-PCE (full name: 2′-Oxo-2-(phenylcyclohexyl)-N-ethyl-ethanamine) is a synthetic compound belonging to the arylcyclohexylamine class — a chemical family best known for substances like PCP (phencyclidine) and ketamine. It is sometimes referred to in research contexts as an arylcyclohexylamine dissociative, because its main pharmacological action is believed to be antagonism of the NMDA (N-methyl-D-aspartate) receptor in the brain.
Chemical Classification and Structure
2′-Oxo-PCE is structurally related to eticyclidine (PCE) but contains a ketone (oxo) group at the 2′ position on the cyclohexyl ring. Its molecular formula is typically reported as C₁₅H₂₁NO, with a molecular weight around 231.33 g/mol. The addition of the oxo group slightly alters its polarity and metabolic profile compared to PCE, while maintaining a similar arylcyclohexylamine core.
Pharmacology
Like other compounds in its class, 2′-Oxo-PCE is thought to work primarily by blocking NMDA receptors, which are involved in excitatory neurotransmission and play key roles in memory, perception, and pain signaling. This blockade can produce dissociation — a sense of detachment from one’s body or surroundings — along with changes in perception, cognition, and mood.
Limited receptor binding data suggest it may also interact with dopamine and sigma receptors, potentially contributing to stimulating or euphoric effects in addition to its dissociative action.
Research and Context
2′-Oxo-PCE is not an approved medication, and its safety, toxicity, and long-term health effects are not well studied in humans. It has appeared on the gray market and in some forensic case reports, often in contexts involving designer dissociatives. Because it is a relatively new compound, most available information comes from analytical chemistry studies, forensic reports, and anecdotal accounts, rather than from controlled pharmacological research.
Legal Status
The legal status of 2′-Oxo-PCE varies internationally. In some countries, it is explicitly controlled as a PCP-type analog or under blanket novel psychoactive substance (NPS) laws. In others, it may be regulated indirectly through analogue acts or chemical control lists.
Summary
2′-Oxo-PCE is a synthetic dissociative arylcyclohexylamine structurally related to PCE and ketamine, believed to act as an NMDA receptor antagonist. It has been detected in designer drug markets but remains poorly studied, with little verified human pharmacology data. Any non-medical use carries unknown health risks, and handling is generally restricted under chemical control regulations.
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