Periodic Acid ACS Reagent 99% 25 Gram
- CAS Number 10450-60-9
- Empirical Formula (Hill Notation) H5IO6
- Molecular Weight 227.94
- EC Number 233-937-0
- MDL number MFCD00011344
- PubChem Substance ID 329755660
- NACRES NA.21
| Grade | ACS reagent |
| Assay | 99% |
| 99.0-101.0% (ACS specification) | |
| Impurities | ≤0.01% insolubles |
| ≤0.01% other halogens | |
| ign. residue | ≤0.01% |
| mp | 122°C (lit.) |
| anion traces | sulfate (SO42-): ≤0.01% |
| cation traces | Fe: ≤0.003% |
| heavy metals: ≤0.005% |
General description
Periodic acid is an inorganic acid commonly used as an oxidizing agent. Periodic acid oxidation Is one of the steps in the periodate-resorcinol assay, used in the determination of sialic acid. Periodic acid reacts with 1,2 glycol linkage of carbohydrates to form aldehydes which can be stained by Schiff™s reagent. Therefore periodic-acid-Schiff²s Reagent (PAS) is used in histochemistry to determine carbohydrates in tissue sections.
Application
Periodic acid may be used in the following reactions
• Oxidation of alcohols to ketones and aldehydes.
• Oxidation hydroxylamine derivatives.
• Oxidation of arenes to quinones.
• Deprotection of the dithio- and oxathio-derivatives.
• Oxidative degradation of epoxidized natural rubber (ENR).
• Oxidation of urazoles and bis-urazoles to triazolinediones.
• Oxidative cleavage of glucosazone.
Signal word Danger
Hazard statements H271-H314-H410
Precautionary statements P210-P260-P280-P305 + P351 + P338-P370 + P378-P371 + P380 + P375
RIDADR UN 3085 8(5.1) / PGII
WGK Germany 3





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